Authors

T Miller¹; PJ McIntyre¹; 
¹ Charnwood Molecular, UK

Discussion

At Charnwood Molecular we believe in the power of SPR to quickly drive drug discovery projects forward and yield critical compound binding data. The ability to triage compounds based on their affinities to a protein target is key for understanding the SAR of a new series and identifying new chemical space to explore.

Equally important is the ability of multiple disciplines to
work together and combine their expertise in an integrated drug discovery
format.

In this work we demonstrate several such of our capabilities
here at Charnwood Molecular:
-SPR assay development for
difficult targets
-Small molecule screening in
multiple different assay formats
-Integrated drug discovery between
different disciplines and departments