Dr Johanna Bolander

My main research interest lies in the investigation of progenitor cells and their regulatory factors during functional and dysfunctional skeletal tissue regeneration. During my PhD, I developed a state of the art in vitro priming regime for human periosteum derived cells which led to superior differentiation and bone forming capacity upon in vitro growth factor stimulation. During my postdoctoral fellowship, I further developed these findings into a hierarchically structured 3D printed fracture callus based on a BMPR2+ progenitor cell population with enhanced bone forming capacity. In order to fully understand the regenerative environment and how this affects the most crucial progenitor cells, I am currently investigating how the inflammatory response from the surrounding environment play a role in tissue regeneration.